Yin-Yang 1 and HBx protein activate HBV transcription by mediating the spatial interaction of cccDNA minichromosome with cellular chromosome 19p13.11

HBV cccDNA stably exists in the nuclei of infected cells as an episomal munichromosome which is responsible for viral persistence and failure of current antiviral treatments. However, the regulatory mechanism of cccDNA transcription by viral and host cellular factors is not well understood. In this...

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Detalles Bibliográficos
Autores principales: Shen, Congle, Feng, Xiaoyu, Mao, Tianhao, Yang, Danli, Zou, Jun, Zao, Xiaobin, Deng, Qiang, Chen, Xiangmei, Lu, Fengmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671595/
https://www.ncbi.nlm.nih.gov/pubmed/33084547
http://dx.doi.org/10.1080/22221751.2020.1840311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671595/
https://www.ncbi.nlm.nih.gov/pubmed/33084547
http://dx.doi.org/10.1080/22221751.2020.1840311

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