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SON and SRRM2 are essential for nuclear speckle formation

Nuclear speckles (NS) are among the most prominent biomolecular condensates. Despite their prevalence, research on the function of NS is virtually restricted to colocalization analyses, since an organizing core, without which NS cannot form, remains unidentified. The monoclonal antibody SC35, raised...

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Detalles Bibliográficos
Autores principales: Ilik, İbrahim Avşar, Malszycki, Michal, Lübke, Anna Katharina, Schade, Claudia, Meierhofer, David, Aktaş, Tuğçe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671692/
https://www.ncbi.nlm.nih.gov/pubmed/33095160
http://dx.doi.org/10.7554/eLife.60579