P2X4R Overexpression Upregulates Interleukin-6 and Exacerbates 6-OHDA-Induced Dopaminergic Degeneration in a Rat Model of PD

The pathogenesis of Parkinson’s disease (PD) remains elusive. Current thinking suggests that the activation of microglia and the subsequent release of inflammatory factors, including interleukin-6 (IL-6), are involved in the pathogenesis of PD. P2X4 receptor (P2X4R) is a member of the P2X superfamil...

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Detalles Bibliográficos
Autores principales: Ma, Jiangnan, Gao, Jinzhao, Niu, Mengyue, Zhang, Xiaona, Wang, Jing, Xie, Anmu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671967/
https://www.ncbi.nlm.nih.gov/pubmed/33328961
http://dx.doi.org/10.3389/fnagi.2020.580068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671967/
https://www.ncbi.nlm.nih.gov/pubmed/33328961
http://dx.doi.org/10.3389/fnagi.2020.580068

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