Genetic background influences expression and function of the cation channel TRPM4 in the mouse heart

Transient receptor potential melastatin 4 (TRPM4) cation channels act in cardiomyocytes as a negative modulator of the L-type Ca(2+) current. Ubiquitous Trpm4 deletion in mice leads to an increased β-adrenergic inotropy in healthy mice as well as after myocardial infarction. In this study, we set ou...

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Detalles Bibliográficos
Autores principales: Medert, Rebekka, Pironet, Andy, Bacmeister, Lucas, Segin, Sebastian, Londoño, Juan E. Camacho, Vennekens, Rudi, Freichel, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671982/
https://www.ncbi.nlm.nih.gov/pubmed/33205255
http://dx.doi.org/10.1007/s00395-020-00831-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671982/
https://www.ncbi.nlm.nih.gov/pubmed/33205255
http://dx.doi.org/10.1007/s00395-020-00831-x

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