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Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation

BACKGROUND: Small bowel vascular malformation disease (SBVM) is the most common cause of obscure gastrointestinal bleeding (OGIB). Several studies suggested that EGFL6 was able to promote the growth of tumor endothelial cells by forming tumor vessels. To date, it remains unclear how EGFL6 promotes p...

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Detalles Bibliográficos
Autores principales: Tang, Chao-Tao, Zhang, Qing-Wei, Wu, Shan, Tang, Ming-Yu, Liang, Qian, Lin, Xiao-Lu, Gao, Yun-Jie, Ge, Zhi-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671996/
https://www.ncbi.nlm.nih.gov/pubmed/32008086
http://dx.doi.org/10.1007/s00018-020-03465-3