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Time, pattern, and outcome of medulloblastoma relapse and their association with tumour biology at diagnosis and therapy: a multicentre cohort study

BACKGROUND: Disease relapse occurs in around 30% of children with medulloblastoma, and is almost universally fatal. We aimed to establish whether the clinical and molecular characteristics of the disease at diagnosis are associated with the nature of relapse and subsequent disease course, and whethe...

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Detalles Bibliográficos
Autores principales: Hill, Rebecca M, Richardson, Stacey, Schwalbe, Edward C, Hicks, Debbie, Lindsey, Janet C, Crosier, Stephen, Rafiee, Gholamreza, Grabovska, Yura, Wharton, Stephen B, Jacques, Thomas S, Michalski, Antony, Joshi, Abhijit, Pizer, Barry, Williamson, Daniel, Bailey, Simon, Clifford, Steven C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671998/
https://www.ncbi.nlm.nih.gov/pubmed/33222802
http://dx.doi.org/10.1016/S2352-4642(20)30246-7