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Optimized Adenoviral Vector That Enhances the Assembly of FMDV O1 Virus-Like Particles in situ Increases Its Potential as Vaccine for Serotype O Viruses

Although replication-defective human adenovirus type 5 (Ad5) vectors that express in situ the capsid-encoding region of foot-and-mouth disease virus (FMDV) have been proven to be effective as vaccines in relevant species for several viral strains, the same result was not consistently achieved for th...

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Detalles Bibliográficos
Autores principales: Ziraldo, Micaela, Bidart, Juan E., Prato, Cecilia A., Tribulatti, María V., Zamorano, Patricia, Mattion, Nora, D’Antuono, Alejandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672010/
https://www.ncbi.nlm.nih.gov/pubmed/33250878
http://dx.doi.org/10.3389/fmicb.2020.591019