Coding Variants Coupled With Rapid Modeling in Zebrafish Implicate Dynein Genes, dnaaf1 and zmynd10, as Adolescent Idiopathic Scoliosis Candidate Genes

Adolescent idiopathic scoliosis (AIS) is the most common pediatric spine disorder affecting ∼3% of children worldwide. Human genetic studies suggest a complex polygenic disease model for AIS with large genetic and phenotypic heterogeneity. However, the overall genetic etiology of AIS remains poorly...

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Detalles Bibliográficos
Autores principales: Wang, Yunjia, Liu, Zhenhao, Yang, Guanteng, Gao, Qile, Xiao, Lige, Li, Jiong, Guo, Chaofeng, Troutwine, Benjamin R., Gray, Ryan S., Xie, Lu, Zhang, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672046/
https://www.ncbi.nlm.nih.gov/pubmed/33251213
http://dx.doi.org/10.3389/fcell.2020.582255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672046/
https://www.ncbi.nlm.nih.gov/pubmed/33251213
http://dx.doi.org/10.3389/fcell.2020.582255

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