Identification of synthetic chemosensitivity genes paired with BRAF for BRAF/MAPK inhibitors

Molecular-targeted approaches are important for personalised cancer treatment, which requires knowledge regarding drug target specificity. Here, we used the synthetic lethality concept to identify candidate gene pairs with synergistic effects on drug responses. A synergistic chemo-sensitivity respon...

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Detalles Bibliográficos
Autores principales: Lee, Kye Hwa, Goh, Jinmin, Kim, Yi-Jun, Kim, Kwangsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672081/
https://www.ncbi.nlm.nih.gov/pubmed/33203961
http://dx.doi.org/10.1038/s41598-020-76909-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672081/
https://www.ncbi.nlm.nih.gov/pubmed/33203961
http://dx.doi.org/10.1038/s41598-020-76909-2

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