Cargando…
Identification of synthetic chemosensitivity genes paired with BRAF for BRAF/MAPK inhibitors
Molecular-targeted approaches are important for personalised cancer treatment, which requires knowledge regarding drug target specificity. Here, we used the synthetic lethality concept to identify candidate gene pairs with synergistic effects on drug responses. A synergistic chemo-sensitivity respon...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672081/ https://www.ncbi.nlm.nih.gov/pubmed/33203961 http://dx.doi.org/10.1038/s41598-020-76909-2 |