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Synaptic migration and reorganization after noise exposure suggests regeneration in a mature mammalian cochlea

Overexposure to intense noise can destroy the synapses between auditory nerve fibers and their hair cell targets without destroying the hair cells themselves. In adult mice, this synaptopathy is immediate and largely irreversible, whereas, in guinea pigs, counts of immunostained synaptic puncta can...

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Detalles Bibliográficos
Autores principales: Hickman, Tyler T., Hashimoto, Ken, Liberman, Leslie D., Liberman, M. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672098/
https://www.ncbi.nlm.nih.gov/pubmed/33203940
http://dx.doi.org/10.1038/s41598-020-76553-w