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The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-β1/NDRG2/MAPK Axis

Liver fibrosis resulting from chronic liver damage constitutes a major health care burden worldwide; however, no antifibrogenic agents are currently available. Our previous study reported that the small molecule NPLC0393 extracted from the herb Gynostemma pentaphyllum exerts efficient antifibrotic e...

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Detalles Bibliográficos
Autores principales: Huang, Hui, Wang, Kuifeng, Liu, Qian, Ji, Feihong, Zhou, Hu, Fang, Shanhua, Zhu, Jiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672159/
https://www.ncbi.nlm.nih.gov/pubmed/33329740
http://dx.doi.org/10.3389/fgene.2020.594824