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Adenoviral-Vectored Mayaro and Chikungunya Virus Vaccine Candidates Afford Partial Cross-Protection From Lethal Challenge in A129 Mouse Model

Mayaro (MAYV) and chikungunya viruses (CHIKV) are vector-borne arthritogenic alphaviruses that cause acute febrile illnesses. CHIKV is widespread and has recently caused large urban outbreaks, whereas the distribution of MAYV is restricted to tropical areas in South America with small and sporadic o...

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Detalles Bibliográficos
Autores principales: Campos, Rafael Kroon, Preciado-Llanes, Lorena, Azar, Sasha R., Kim, Young Chan, Brandon, Olivia, López-Camacho, César, Reyes-Sandoval, Arturo, Rossi, Shannan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672187/
https://www.ncbi.nlm.nih.gov/pubmed/33224148
http://dx.doi.org/10.3389/fimmu.2020.591885