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Alpha-Arbutin Promotes Wound Healing by Lowering ROS and Upregulating Insulin/IGF-1 Pathway in Human Dermal Fibroblast

Alpha-arbutin (4-hydroxyphenyl alpha-glucopyranoside) is a known inhibitor of tyrosinase in keratinocytes; however, its effect on other genes and pathways in other skin cells has not been thoroughly investigated. In this study, we investigate the mechanism of alpha-arbutin activity in human dermal f...

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Detalles Bibliográficos
Autores principales: Polouliakh, Natalia, Ludwig, Vanessa, Meguro, Akira, Kawagoe, Tatsukata, Heeb, Oliver, Mizuki, Nobuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672191/
https://www.ncbi.nlm.nih.gov/pubmed/33250779
http://dx.doi.org/10.3389/fphys.2020.586843