TMEPAI/PMEPA1 Is a Positive Regulator of Skeletal Muscle Mass

Inhibition of myostatin- and activin-mediated SMAD2/3 signaling using ligand traps, such as soluble receptors, ligand-targeting propeptides and antibodies, or follistatin can increase skeletal muscle mass in healthy mice and ameliorate wasting in models of cancer cachexia and muscular dystrophy. How...

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Detalles Bibliográficos
Autores principales: Hagg, Adam, Kharoud, Swati, Goodchild, Georgia, Goodman, Craig A., Chen, Justin L., Thomson, Rachel E., Qian, Hongwei, Gregorevic, Paul, Harrison, Craig A., Walton, Kelly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672205/
https://www.ncbi.nlm.nih.gov/pubmed/33250771
http://dx.doi.org/10.3389/fphys.2020.560225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672205/
https://www.ncbi.nlm.nih.gov/pubmed/33250771
http://dx.doi.org/10.3389/fphys.2020.560225

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