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New developments in Huntington’s disease and other triplet repeat diseases: DNA repair turns to the dark side
Huntington’s disease (HD) is a fatal, inherited neurodegenerative disease that causes neuronal death, particularly in medium spiny neurons. HD leads to serious and progressive motor, cognitive and psychiatric symptoms. Its genetic basis is an expansion of the CAG triplet repeat in the HTT gene, lead...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672267/ https://www.ncbi.nlm.nih.gov/pubmed/33224521 http://dx.doi.org/10.1042/NS20200010 |