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New developments in Huntington’s disease and other triplet repeat diseases: DNA repair turns to the dark side

Huntington’s disease (HD) is a fatal, inherited neurodegenerative disease that causes neuronal death, particularly in medium spiny neurons. HD leads to serious and progressive motor, cognitive and psychiatric symptoms. Its genetic basis is an expansion of the CAG triplet repeat in the HTT gene, lead...

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Detalles Bibliográficos
Autor principal:	Lahue, Robert S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Molecular Bases of Health & Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672267/ https://www.ncbi.nlm.nih.gov/pubmed/33224521 http://dx.doi.org/10.1042/NS20200010

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