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Association of ALDH1A1-NEK-2 axis in cisplatin resistance in ovarian cancer cells

Development of acquired resistance to cisplatin (CDDP) is a major obstacle in the treatment of ovarian cancer patients. According to the cancer stem cell (CSC) hypothesis, the recurrence and chemoresistance are presumed to be linked to cancer stem/progenitor cells. Here, we investigated the CSC-like...

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Detalles Bibliográficos
Autores principales: Uddin, Md. Hafiz, Kim, Boyun, Cho, Untack, Azmi, Asfar S., Song, Yong Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672295/
https://www.ncbi.nlm.nih.gov/pubmed/33241139
http://dx.doi.org/10.1016/j.heliyon.2020.e05442