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Simvastatin Suppresses Human Breast Cancer Cell Invasion by Decreasing the Expression of Pituitary Tumor-Transforming Gene 1

Statins, or 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, have been widely used to lower cholesterol and prevent cardiovascular diseases. Recent preclinical and clinical studies have shown that statins exert beneficial effects in the management of breast cancer, while the underlying me...

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Detalles Bibliográficos
Autores principales: Yin, Litian, He, Zhongmei, Yi, Bing, Xue, Linyuan, Sun, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672329/
https://www.ncbi.nlm.nih.gov/pubmed/33250768
http://dx.doi.org/10.3389/fphar.2020.574068