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Conditional guide RNA through two intermediate hairpins for programmable CRISPR/Cas9 function: building regulatory connections between endogenous RNA expressions

A variety of nanodevices developed for nucleic acid computation provide great opportunities to construct versatile synthetic circuits for manipulation of gene expressions. In our study, by employing a two-hairpin mediated nucleic acid strand displacement as a processing joint for conditional guide R...

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Detalles Bibliográficos
Autores principales: Lin, Jiao, Liu, Yan, Lai, Peidong, Ye, Huixia, Xu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672423/
https://www.ncbi.nlm.nih.gov/pubmed/33068434
http://dx.doi.org/10.1093/nar/gkaa842