Cell cycle regulated DNA methyltransferase: fluorescent tracking of a DNA strand-separation mechanism and identification of the responsible protein motif

DNA adenine methylation by Caulobacter crescentus Cell Cycle Regulated Methyltransferase (CcrM) is an important epigenetic regulator of gene expression. The recent CcrM-DNA cocrystal structure shows the CcrM dimer disrupts four of the five base pairs of the (5′-GANTC-3′) recognition site. We develop...

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Detalles Bibliográficos
Autores principales: Konttinen, Olivia, Carmody, Jason, Pathuri, Sarath, Anderson, Kyle, Zhou, Xiaofeng, Reich, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672430/
https://www.ncbi.nlm.nih.gov/pubmed/33053173
http://dx.doi.org/10.1093/nar/gkaa844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672430/
https://www.ncbi.nlm.nih.gov/pubmed/33053173
http://dx.doi.org/10.1093/nar/gkaa844

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