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NMR structure of a vestigial nuclease provides insight into the evolution of functional transitions in viral dsDNA packaging motors

Double-stranded DNA viruses use ATP-powered molecular motors to package their genomic DNA. To ensure efficient genome encapsidation, these motors regulate functional transitions between initiation, translocation, and termination modes. Here, we report structural and biophysical analyses of the C-ter...

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Detalles Bibliográficos
Autores principales: Mahler, Bryon P, Bujalowski, Paul J, Mao, Huzhang, Dill, Erik A, Jardine, Paul J, Choi, Kyung H, Morais, Marc C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672431/
https://www.ncbi.nlm.nih.gov/pubmed/33089330
http://dx.doi.org/10.1093/nar/gkaa874