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Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2

RNA-binding proteins (RBPs) are key mediators of RNA metabolism. Whereas some RBPs exhibit narrow transcript specificity, others function broadly across both coding and non-coding RNAs. Here, in Saccharomyces cerevisiae, we demonstrate that changes in RBP availability caused by disruptions to distin...

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Detalles Bibliográficos
Autores principales: Aguilar, Lisbeth-Carolina, Paul, Biplab, Reiter, Taylor, Gendron, Louis, Arul Nambi Rajan, Arvind, Montpetit, Rachel, Trahan, Christian, Pechmann, Sebastian, Oeffinger, Marlene, Montpetit, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672433/
https://www.ncbi.nlm.nih.gov/pubmed/33137177
http://dx.doi.org/10.1093/nar/gkaa964