Importance of base-pair opening for mismatch recognition

Mismatch repair is a highly conserved cellular pathway responsible for repairing mismatched dsDNA. Errors are detected by the MutS enzyme, which most likely senses altered mechanical property of damaged dsDNA rather than a specific molecular pattern. While the curved shape of dsDNA in crystallograph...

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Detalles Bibliográficos
Autores principales: Bouchal, Tomáš, Durník, Ivo, Illík, Viktor, Réblová, Kamila, Kulhánek, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672436/
https://www.ncbi.nlm.nih.gov/pubmed/33080020
http://dx.doi.org/10.1093/nar/gkaa896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672436/
https://www.ncbi.nlm.nih.gov/pubmed/33080020
http://dx.doi.org/10.1093/nar/gkaa896

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