Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases

Removal of ribonucleotides (rNMPs) incorporated into the genome by the ribonucleotide excision repair (RER) is essential to avoid genetic instability. In eukaryotes, the RNaseH2 is the only known enzyme able to incise 5′ of the rNMP, starting the RER process, which is subsequently carried out by rep...

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Detalles Bibliográficos
Autores principales: Riva, Valentina, Garbelli, Anna, Casiraghi, Federica, Arena, Francesca, Trivisani, Claudia Immacolata, Gagliardi, Assunta, Bini, Luca, Schroeder, Martina, Maffia, Antonio, Sabbioneda, Simone, Maga, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672437/
https://www.ncbi.nlm.nih.gov/pubmed/33137198
http://dx.doi.org/10.1093/nar/gkaa948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672437/
https://www.ncbi.nlm.nih.gov/pubmed/33137198
http://dx.doi.org/10.1093/nar/gkaa948

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