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Sperm histone H3 lysine 4 trimethylation is altered in a genetic mouse model of transgenerational epigenetic inheritance

Advancing the molecular knowledge surrounding fertility and inheritance has become critical given the halving of sperm counts in the last 40 years, and the rise in complex disease which cannot be explained by genetics alone. The connection between both these trends may lie in alterations to the sper...

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Detalles Bibliográficos
Autores principales: Lismer, Ariane, Siklenka, Keith, Lafleur, Christine, Dumeaux, Vanessa, Kimmins, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672453/
https://www.ncbi.nlm.nih.gov/pubmed/33068438
http://dx.doi.org/10.1093/nar/gkaa712