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Inhibition of Plasmodium falciparum Lysyl-tRNA synthetase via an anaplastic lymphoma kinase inhibitor

Aminoacyl-tRNA synthetases are attractive targets for the development of antibacterial, antifungal, antiparasitic agents and for the treatment of other human diseases. Lysyl-tRNA synthetase (LysRS) from this family has been validated as a promising target for the development of antimalarial drugs. H...

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Detalles Bibliográficos
Autores principales: Zhou, Jintong, Huang, Zhenghui, Zheng, Li, Hei, Zhoufei, Wang, Zhiyong, Yu, Biao, Jiang, Lubin, Wang, Jing, Fang, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672456/
https://www.ncbi.nlm.nih.gov/pubmed/33053158
http://dx.doi.org/10.1093/nar/gkaa862