EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma

Core regulatory circuitry (CRC)-dependent transcriptional network is critical for developmental tumors in children and adolescents carrying few gene mutations. However, whether and how CRC contributes to transcription regulation in Ewing sarcoma is unknown. Here, we identify and functionally validat...

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Detalles Bibliográficos
Autores principales: Shi, Xianping, Zheng, Yueyuan, Jiang, Liling, Zhou, Bo, Yang, Wei, Li, Liyan, Ding, Lingwen, Huang, Moli, Gery, Sigal, Lin, De-Chen, Koeffler, H Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672457/
https://www.ncbi.nlm.nih.gov/pubmed/33080033
http://dx.doi.org/10.1093/nar/gkaa901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672457/
https://www.ncbi.nlm.nih.gov/pubmed/33080033
http://dx.doi.org/10.1093/nar/gkaa901

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