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EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma
Core regulatory circuitry (CRC)-dependent transcriptional network is critical for developmental tumors in children and adolescents carrying few gene mutations. However, whether and how CRC contributes to transcription regulation in Ewing sarcoma is unknown. Here, we identify and functionally validat...
Autores principales: | Shi, Xianping, Zheng, Yueyuan, Jiang, Liling, Zhou, Bo, Yang, Wei, Li, Liyan, Ding, Lingwen, Huang, Moli, Gery, Sigal, Lin, De-Chen, Koeffler, H Phillip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672457/ https://www.ncbi.nlm.nih.gov/pubmed/33080033 http://dx.doi.org/10.1093/nar/gkaa901 |
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