Cargando…

Detection of genomic G-quadruplexes in living cells using a small artificial protein

G-quadruplex (G4) structures formed by guanine-rich nucleic acids are implicated in essential physiological and pathological processes and serve as important drug targets. The genome-wide detection of G4s in living cells is important for exploring the functional role of G4s but has not yet been achi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Ke-wei, Zhang, Jia-yu, He, Yi-de, Gong, Jia-yuan, Wen, Cui-jiao, Chen, Juan-nan, Hao, Yu-hua, Zhao, Yong, Tan, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672459/
https://www.ncbi.nlm.nih.gov/pubmed/33045726
http://dx.doi.org/10.1093/nar/gkaa841