Benchmarking and integrating genome-wide CRISPR off-target detection and prediction

Systematic evaluation of genome-wide Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) off-target profiles is a fundamental step for the successful application of the CRISPR system to clinical therapies. Many experimental techniques and in silico tools have been proposed for detecti...

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Detalles Bibliográficos
Autores principales: Yan, Jifang, Xue, Dongyu, Chuai, Guohui, Gao, Yuli, Zhang, Gongchen, Liu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672467/
https://www.ncbi.nlm.nih.gov/pubmed/33137817
http://dx.doi.org/10.1093/nar/gkaa930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672467/
https://www.ncbi.nlm.nih.gov/pubmed/33137817
http://dx.doi.org/10.1093/nar/gkaa930

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