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Ensemble-Based Analysis of the Dynamic Allostery in the PSD-95 PDZ3 Domain in Relation to the General Variability of PDZ Structures

PDZ domains are abundant interaction hubs found in a number of different proteins and they exhibit characteristic differences in their structure and ligand specificity. Their internal dynamics have been proposed to contribute to their biological activity via changes in conformational entropy upon li...

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Detalles Bibliográficos
Autores principales: Dudola, Dániel, Hinsenkamp, Anett, Gáspári, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672539/
https://www.ncbi.nlm.nih.gov/pubmed/33172212
http://dx.doi.org/10.3390/ijms21218348