Copper Ionophores as Novel Antiobesity Therapeutics

The therapeutic utility of the copper ionophore disulfiram was investigated in a diet-induced obesity mouse model (C57BL/6J background), both through administration in feed (0.05 to 1% (w/w)) and via oral gavage (150 mg/kg) for up to eight weeks. Mice were monitored for body weight, fat deposition (...

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Detalles Bibliográficos
Autores principales: Meggyesy, Peter M., Masaldan, Shashank, Clatworthy, Sharnel A. S., Volitakis, Irene, Eyckens, Daniel J., Aston-Mourney, Kathryn, Cater, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672559/
https://www.ncbi.nlm.nih.gov/pubmed/33120881
http://dx.doi.org/10.3390/molecules25214957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672559/
https://www.ncbi.nlm.nih.gov/pubmed/33120881
http://dx.doi.org/10.3390/molecules25214957

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