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Copper Ionophores as Novel Antiobesity Therapeutics
The therapeutic utility of the copper ionophore disulfiram was investigated in a diet-induced obesity mouse model (C57BL/6J background), both through administration in feed (0.05 to 1% (w/w)) and via oral gavage (150 mg/kg) for up to eight weeks. Mice were monitored for body weight, fat deposition (...
Autores principales: | Meggyesy, Peter M., Masaldan, Shashank, Clatworthy, Sharnel A. S., Volitakis, Irene, Eyckens, Daniel J., Aston-Mourney, Kathryn, Cater, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672559/ https://www.ncbi.nlm.nih.gov/pubmed/33120881 http://dx.doi.org/10.3390/molecules25214957 |
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