Coevolution, Dynamics and Allostery Conspire in Shaping Cooperative Binding and Signal Transmission of the SARS-CoV-2 Spike Protein with Human Angiotensin-Converting Enzyme 2

Binding to the host receptor is a critical initial step for the coronavirus SARS-CoV-2 spike protein to enter into target cells and trigger virus transmission. A detailed dynamic and energetic view of the binding mechanisms underlying virus entry is not fully understood and the consensus around the...

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Detalles Bibliográficos
Autor principal: Verkhivker, Gennady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672574/
https://www.ncbi.nlm.nih.gov/pubmed/33158276
http://dx.doi.org/10.3390/ijms21218268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672574/
https://www.ncbi.nlm.nih.gov/pubmed/33158276
http://dx.doi.org/10.3390/ijms21218268

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