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ITGA6+ Human Testicular Cell Populations Acquire a Mesenchymal Rather than Germ Cell Transcriptional Signature during Long-Term Culture

Autologous spermatogonial stem cell transplantation is an experimental technique aimed at restoring fertility in infertile men. Although effective in animal models, in vitro propagation of human spermatogonia prior to transplantation has proven to be difficult. A major limiting factor is endogenous...

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Detalles Bibliográficos
Autores principales: Struijk, Robert B., Mulder, Callista L., van Daalen, Saskia K. M., de Winter-Korver, Cindy M., Jongejan, Aldo, Repping, Sjoerd, van Pelt, Ans M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672582/
https://www.ncbi.nlm.nih.gov/pubmed/33158248
http://dx.doi.org/10.3390/ijms21218269