Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/Bis-2(1H)-Quinolinone Hybrids

A series of novel 1,2,3-triazoles hybridized with two quinolin-2-ones, was designed and synthesized through click reactions. The structures of the synthesized compounds were elucidated by NMR, IR, and mass spectra in addition to elemental analysis. The synthesized compounds were assessed for their a...

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Detalles Bibliográficos
Autores principales: El-Sheref, Essmat M., Aly, Ashraf A., Alshammari, Mohammed B., Brown, Alan B., Abdel-Hafez, Sara Mohamed Naguib, Abdelzaher, Walaa Yehia, Bräse, Stefan, Abdelhafez, ElShimaa M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672604/
https://www.ncbi.nlm.nih.gov/pubmed/33143331
http://dx.doi.org/10.3390/molecules25215057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672604/
https://www.ncbi.nlm.nih.gov/pubmed/33143331
http://dx.doi.org/10.3390/molecules25215057

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