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The Loss of HLA-F/KIR3DS1 Ligation Is Mediated by Hemoglobin Peptides

The human leukocyte antigen (HLA)-Ib molecule, HLA-F, is known as a CD4(+) T-cell protein and mediator of HIV progression. While HLA-Ia molecules do not have the chance to select and present viral peptides for immune recognition due to protein downregulation, HLA-F is upregulated. Post HIV infection...

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Detalles Bibliográficos
Autores principales: Hò, Gia-Gia T., Hiemisch, Wiebke, Pich, Andreas, Behrens, Georg M. N., Blasczyk, Rainer, Bade-Doeding, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672607/
https://www.ncbi.nlm.nih.gov/pubmed/33126487
http://dx.doi.org/10.3390/ijms21218012