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HiC-Hiker: a probabilistic model to determine contig orientation in chromosome-length scaffolds with Hi-C

MOTIVATION: De novo assembly of reference-quality genomes used to require enormously laborious tasks. In particular, it is extremely time-consuming to build genome markers for ordering assembled contigs along chromosomes; thus, they are only available for well-established model organisms. To resolve...

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Detalles Bibliográficos
Autores principales: Nakabayashi, Ryo, Morishita, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672694/
https://www.ncbi.nlm.nih.gov/pubmed/32369554
http://dx.doi.org/10.1093/bioinformatics/btaa288