The MOBSTER R package for tumour subclonal deconvolution from bulk DNA whole-genome sequencing data

BACKGROUND: The large-scale availability of whole-genome sequencing profiles from bulk DNA sequencing of cancer tissues is fueling the application of evolutionary theory to cancer. From a bulk biopsy, subclonal deconvolution methods are used to determine the composition of cancer subpopulations in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Caravagna, Giulio, Sanguinetti, Guido, Graham, Trevor A., Sottoriva, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672894/
https://www.ncbi.nlm.nih.gov/pubmed/33203356
http://dx.doi.org/10.1186/s12859-020-03863-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672894/
https://www.ncbi.nlm.nih.gov/pubmed/33203356
http://dx.doi.org/10.1186/s12859-020-03863-1

Ejemplares similares