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The MOBSTER R package for tumour subclonal deconvolution from bulk DNA whole-genome sequencing data

BACKGROUND: The large-scale availability of whole-genome sequencing profiles from bulk DNA sequencing of cancer tissues is fueling the application of evolutionary theory to cancer. From a bulk biopsy, subclonal deconvolution methods are used to determine the composition of cancer subpopulations in t...

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Detalles Bibliográficos
Autores principales:	Caravagna, Giulio, Sanguinetti, Guido, Graham, Trevor A., Sottoriva, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Software
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672894/ https://www.ncbi.nlm.nih.gov/pubmed/33203356 http://dx.doi.org/10.1186/s12859-020-03863-1

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