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The tumor suppressor Zinc finger protein 471 suppresses breast cancer growth and metastasis through inhibiting AKT and Wnt/β-catenin signaling

BACKGROUND: Zinc-finger protein 471 (ZNF471) is a member of the Krüppel-associated box domain zinc finger protein (KRAB-ZFP) family. ZNF471 is methylated in squamous cell carcinomas of tongue, stomach and esophageal. However, its role in breast carcinogenesis remains elusive. Here, we studied its ex...

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Detalles Bibliográficos
Autores principales: Tao, Chunfang, Luo, Juan, Tang, Jun, Zhou, Danfeng, Feng, Shujun, Qiu, Zhu, Putti, Thomas C., Xiang, Tingxiu, Tao, Qiao, Li, Lili, Ren, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672945/
https://www.ncbi.nlm.nih.gov/pubmed/33203470
http://dx.doi.org/10.1186/s13148-020-00959-6