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Exosome-transferred hsa_circ_0014235 promotes DDP chemoresistance and deteriorates the development of non-small cell lung cancer by mediating the miR-520a-5p/CDK4 pathway

BACKGROUND: Circular RNAs (circRNAs) play crucial roles in the development and progression of human cancers, including non-small cell lung cancer (NSCLC). However, most of these circRNAs, such as hsa_circ_0014235, are not fully identified in functions and mechanisms. METHODS: The isolated exosomes f...

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Detalles Bibliográficos
Autores principales: Xu, Xueliang, Tao, Rong, Sun, Liying, Ji, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672955/
https://www.ncbi.nlm.nih.gov/pubmed/33292236
http://dx.doi.org/10.1186/s12935-020-01642-9