Inhibition of pyruvate dehydrogenase kinase influence microbiota and metabolomic profile in pancreatic cancer xenograft mice

OBJECTIVE: Despite recent advances in treatment options, pancreatic cancer remains the most deadly major cancer. Targeting metabolism represents an emerging anti-cancer strategy. RESULTS: Metagenomic 16S analysis was employed to explore the effect of Dichloroacetate (DCA) on the composition of the f...

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Detalles Bibliográficos
Autores principales: Adamberg, Kaarel, Vilu, Raivo, Pazienza, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672971/
https://www.ncbi.nlm.nih.gov/pubmed/33208188
http://dx.doi.org/10.1186/s13104-020-05384-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672971/
https://www.ncbi.nlm.nih.gov/pubmed/33208188
http://dx.doi.org/10.1186/s13104-020-05384-9

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