Cargando…

A computational diffusion model to study antibody transport within reconstructed tumor microenvironments

BACKGROUND: Antibodies revolutionized cancer treatment over the past decades. Despite their successfully application, there are still challenges to overcome to improve efficacy, such as the heterogeneous distribution of antibodies within tumors. Tumor microenvironment features, such as the distribut...

Descripción completa

Detalles Bibliográficos
Autores principales: Cartaxo, Ana Luísa, Almeida, Jaime, Gualda, Emilio J., Marsal, Maria, Loza-Alvarez, Pablo, Brito, Catarina, Isidro, Inês A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672975/
https://www.ncbi.nlm.nih.gov/pubmed/33203360
http://dx.doi.org/10.1186/s12859-020-03854-2