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A computational diffusion model to study antibody transport within reconstructed tumor microenvironments
BACKGROUND: Antibodies revolutionized cancer treatment over the past decades. Despite their successfully application, there are still challenges to overcome to improve efficacy, such as the heterogeneous distribution of antibodies within tumors. Tumor microenvironment features, such as the distribut...
Autores principales: | Cartaxo, Ana Luísa, Almeida, Jaime, Gualda, Emilio J., Marsal, Maria, Loza-Alvarez, Pablo, Brito, Catarina, Isidro, Inês A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672975/ https://www.ncbi.nlm.nih.gov/pubmed/33203360 http://dx.doi.org/10.1186/s12859-020-03854-2 |
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