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A ribosome-associated chaperone enables substrate triage in a cotranslational protein targeting complex

Protein biogenesis is essential in all cells and initiates when a nascent polypeptide emerges from the ribosome exit tunnel, where multiple ribosome-associated protein biogenesis factors (RPBs) direct nascent proteins to distinct fates. How distinct RPBs spatiotemporally coordinate with one another...

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Detalles Bibliográficos
Autores principales: Hsieh, Hao-Hsuan, Lee, Jae Ho, Chandrasekar, Sowmya, Shan, Shu-ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673040/
https://www.ncbi.nlm.nih.gov/pubmed/33203865
http://dx.doi.org/10.1038/s41467-020-19548-5