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A ribosome-associated chaperone enables substrate triage in a cotranslational protein targeting complex
Protein biogenesis is essential in all cells and initiates when a nascent polypeptide emerges from the ribosome exit tunnel, where multiple ribosome-associated protein biogenesis factors (RPBs) direct nascent proteins to distinct fates. How distinct RPBs spatiotemporally coordinate with one another...
Autores principales: | Hsieh, Hao-Hsuan, Lee, Jae Ho, Chandrasekar, Sowmya, Shan, Shu-ou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673040/ https://www.ncbi.nlm.nih.gov/pubmed/33203865 http://dx.doi.org/10.1038/s41467-020-19548-5 |
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