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Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting

Exploring the molecular mechanisms that prevent inflammation during caloric restriction may yield promising therapeutic targets. During fasting, activation of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) promotes the utilization of lipids as an energy source. Herein, we...

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Detalles Bibliográficos
Autores principales: Brocker, Chad N., Kim, Donghwan, Melia, Tisha, Karri, Kritika, Velenosi, Thomas J., Takahashi, Shogo, Aibara, Daisuke, Bonzo, Jessica A., Levi, Moshe, Waxman, David J., Gonzalez, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673042/
https://www.ncbi.nlm.nih.gov/pubmed/33203882
http://dx.doi.org/10.1038/s41467-020-19554-7