The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases

GPR37L1 is an orphan G protein-coupled receptor expressed exclusively in the brain and linked to seizures, neuroprotection and cardiovascular disease. Based upon the observation that fragments of the GPR37L1 N-terminus are found in human cerebrospinal fluid, we hypothesized that GPR37L1 was subject...

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Detalles Bibliográficos
Autores principales: Coleman, James L. J., Ngo, Tony, Smythe, Rhyll E., Cleave, Andrew J., Jones, Nicole M., Graham, Robert M., Smith, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673139/
https://www.ncbi.nlm.nih.gov/pubmed/33203955
http://dx.doi.org/10.1038/s41598-020-76384-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673139/
https://www.ncbi.nlm.nih.gov/pubmed/33203955
http://dx.doi.org/10.1038/s41598-020-76384-9

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